Well obviously it's okay with a question:
Which of the dogs was ill?
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I would do it in a non-question sentence, but only if I really wanted to emphasise it.
I went running along the road looking for the dog. Which was lost and had been missing for hours. I found her in a ditch |
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just makes the writer look ignorant. But - say -
So, we've proved that only person who could have killed John in Dover at least an hour before he was found at 4.15, was Alice. And we know that Alice was seen in a café in Honfleur at 6.45, so she must have taken less than two and a half hours to cross the Channel. Which is impossible. |
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might well work, because it suits the way that it would be said. Narrative in fiction always has one foot in how people actually speak, after all - and sentence structures have to reflect that, as well as grammatical correctness.
<Added>Crossed with Jem. Yes, exactly.