I have to agree with him. I can spot a self-published cover a mile off - as can most people. However, it's often not the image used, but the font.
I've just been on Facebook, looking at an author's page which used a book cover for the profile image. The image was fine. The font screamed self-published.
A friend also self-published. She asked me what I thought of her cover and I suggested she changed the font. Comic Sans is not a good look for a cover, nor for anything other than children's school work. But Comic Sans it is, because she likes it.
I agree with his comment about editing too. If I ever took the self-publishing route, I would pay to have my work edited. Not only because I have respect, but what if one day I finally get published and someone locates my unedited rubbish on the internet.
<Added>Just noticed it was written before the Kindle/epublishing took off - but the message is still valid.
Love the author asking if the blog posting relates to him, then linking to this:
http://meandmybigmouth.typepad.com/scottpack/2007/02/muslim_toast.html