Dee, we might eventually get a giant house rabbit - our rabbit kennels have got a couple and they are
huge! Very affectionate - mind you, you'd have a job lifting one up!
Normal size rabbits are very easy, though, i believe and is something else we might consider - as long as you put protective covering around any cable - as for general gnawing, i suspect if you get one young enough you could easily train it eg by squirting water. And just find somewhere for the litter tray - i believe, again, they are easy to train for poos - we had an outdoor one which always pooed in the same place and not in its bedding.
I'm sure someone on this site has an indoor one - is it Naomi?
We would let our outdoors ones in, but apparently, in the winter, the change of temperature from in to out to in isn't good for them and could make them ill.
Casey
<Added>So, you might need a litter tray for the winter, Dee, but could probably let it out easily enough in the summer