I've spent some time querying by emails to various agents, trying to find out the best person to send my MS to.
Some have not responded and I wondered how important is to be able to approach a name as opposed to a submissions department?

I'd move heaven and earth to get one, Lola. A quick phone call before you submit your work usually does the job, and then it means your ms is landing on the right desk. Your covering letter will also create a better impression if it's addressed to a named person.

Good luck!

It's really important to target your submissions to agents who deal with the genre you are writing in. Research an agency's website and find out what kind of authors they represent, then find the names of the specific agents. Some agents for example, have expertise in breaking first-time authors (Jonny Geller, for example), others have a special interest in children's fiction - it's crucial to show that you know what kind of fiction the agent currently represents - otherwise, unless your fiction is mindblowing, you stand a slim chance of getting representation. The acknowledgement pages in books is a good place to look. Or keep an eye out on Bookseller for the agents who are currently making deals - they are more likely to be looking for new clients. Hope this is helpful.

Thanks, i have a few names- gleaned from the acknowledgement pages of my favourite authors.
Others I have emailed the agency and asked for the appropriate name.

My first submissions went out this morning! Eek!

Very good luck with it!

Emma